A First-in-Class Nasal Airway Device

Redefining Airway Management for all healthcare settings
Fast, Safe, and Ready to Scale in a $4B+ Global Market

AMtubation Nasal Airway Device in Use

Transformational Market Opportunity

Positioned to capture significant share in a rapidly growing market

$2.5B
U.S. Market 2024

Current nasal intubation device market valuation

$4.1B
Projected by 2033

7.2% CAGR growth trajectory

$7B+
Global Market

Broader airway management market annually

The Problem
Critical Limitations with Current Solutions

  • → Risk of Trauma: Current ETTs often cause damage to vocal cords, trachea, and surrounding tissues
  • → Infection & Aspiration: Micro-aspiration leads to ventilator-associated pneumonia (VAP)—a costly complication
  • → Time-Sensitive Challenges: Emergency intubation delays can cause morbidity and mortality
  • → Specialized Skills Required: Limited trained personnel in pre-hospital and battlefield settings
  • → Patient Burden: Prolonged ICU stays significantly increase healthcare costs

Our target market extends from field use to military

EMT & ambulatory

Oral surgery

Plastic surgery

Emergency medicine

Veterinarian medicine

Military

U.S. Healthcare Cost Savings
Nasal Tubes vs Paralytics

Healthcare Benefit Estimated Savings
1. Avoiding Paralytic Drugs $100M — $300M/year
2. Shorter ICU Stays (Less Ventilation) $350M — $1B/year
3. Avoiding Complications (Neuropathy, Vocal Cord) $200M — $500M/year
4. Avoiding Sedation-Related Complications (Delirium) $200M — $2B/year
TOTAL ANNUAL SAVINGS $850M — $3.8B/year

Anesthesia Pricing Sheet

General Anesthesia (GA) Price
Nasal $1.80
IV 20g $2.20
500 mL NS 0.9% $3.80
IV tubing $1.80
IV tubing extension $2.00
Propofol 200mg vial x 2 $2.80
Zofran 4mg vial $0.40
Fentanyl 100mg vial $0.85
Ancef 1g vial $1.10
Rocuronium 50mg vial x 1 $8.60
Neostigmine 10mg vial x 1 $4.85
Glycopyrrolate 0.2 mg vial x 3 $10.20
Fentanyl 100mg vial x 2 $1.70
Sevoflurane vial x 1 $105.50
Dantrolene *required in the room, not to be used** $924.30
Nasal ET tube #7 $7.30
Ventilation circuit $9.45
McGills (?)
Intubation blades $185
ETT extension accordion (?)
Totals: $1,276.50

Cost Analysis Paralytic-Use Impact

Medium Paralytic-Use Scenario (Recommended Central Estimate)

Paralytic use: 40% of 40,000,000 → 16,000,000 cases using paralytics/year.

Clinically-significant complication rate: 0.5% of paralytic cases → 80,000 complications/year.

Annual Cost Depending on Per-Complication Cost:

  • If per-complication = $20,000$1.60 billion / year
  • If per-complication = $62,000 (anchor) → $4.96 billion / year
  • If per-complication = $100,000$8.00 billion / year
Interpretation: With medium assumptions, the modeled annual US cost attributable to paralytic-related/intubation major complications is approximately $1.6B — $8.0B, with a central anchor near $4.96B using $62k per event.

Assumed Share of Paralytic-Using Cases (Example Allocation)

30%
Ambulatory (ASC / Hospital Outpatient)
5%
Oral/Maxillofacial Surgery
5%
Plastic / Cosmetic Surgery
10%
ENT / Otolaryngology
3%
DoD / Military Health System
47%
Other Hospitals / OB / Major Inpatient Surgeries

Distribution of 80,000 Total Complications/Year by Setting

Setting Share Complications Annual Cost
Ambulatory 30% 24,000 $1.488 billion/year
Oral / Maxillofacial 5% 4,000 $248 million/year
Plastic / Cosmetic 5% 4,000 $248 million/year
ENT 10% 8,000 $496 million/year
DoD 3% 2,400 $148.8 million/year
Other 47% 37,600 $2.3312 billion/year
Total ≈ $4.96 billion

Meet the Inventor & Founder

Alexander Guizzotti

Alexander Guizzotti

Co-Founder & CEO, Amnea Corp

Alexander Guizzotti is the visionary inventor behind AMtubation®, holding 3 U.S. Patents for this revolutionary nasal airway technology.

Working alongside Dr. Uday Reebye in surgical centers from 2019-2023, Alexander led the development through 3 years of rigorous surgical trials. From 2023-2025, Alexander transformed an innovative concept into a patient-safe, commercially-ready prototype to manufacture, changing the landscape of healthcare.

His dedication to solving critical challenges in airway management, resulted due to his mother being diagnosed with cancer. The relentless pursuit to ensure his mother would live, created the environment in oral surgery and anesthesia which lead to a first-in-class device promising to revolutionize emergency medicine, anesthesia, and surgical procedures worldwide.

Leadership Team

World-Class Experts Driving Innovation in Airway Management

Dr. Andrew Chen

Dr. Andrew Chen

Anesthesiologist

Diplomate of the National Dental Board of Anesthesiology and Fellow of the American Society of Dental Anesthesiology. Assistant Professor at USC School of Dentistry.

Dr. Steven Greco

Dr. Steven Greco

Dentist to the Stars

Graduate of Case Western Reserve School of Dentistry and F.A.C.E. Institute. Renowned for world-class cosmetic and reconstructive dentistry with decades of expertise.

Dr. Bruce Wright

Dr. Bruce Wright

Pediatric Emergency Medicine

Completed emergency medicine fellowship at Cincinnati Children's Hospital. Associate Professor at Stollery Children's Hospital with extensive pediatric emergency expertise.

Distinguished Clinical Approvals

Backed by Leading Physicians and Key Opinion Leaders

Published Research

"Nasopharyngeal passage and supraglottic placement of a 5.0 oral endotracheal tube for management of difficult airways during office-based procedural sedation"

Dowsett, Khan, Souza, Reebye, et al. - National Publication

Advanced Technology Platform

Patented Innovation Designed for Superior Clinical Outcomes

Rapid Airway Security

Placement achieved within seconds in clinical trials

🎯

Supraglottic Placement

Nasal route above the cords for minimal invasiveness

💨

Positive Pressure Ventilation

Full ventilation support with secure seal

🔬

Tri-Lumen Design

Suction and drug delivery when IV access delayed

Ease of Use

Designed for various provider skill levels

🛡️

Patent Protected

Robust IP estate with utility and design patents

🏥

Multi-Sector Applications

ENT, Emergency, Military, Pediatrics, Veterinary

📋

FDA Class I

510(k) exempt status - rapid path to market

Competitive Advantage

AMtubation® vs. Industry Standards

Feature Competitors AMtubation®
Nasal Tube as Endotracheal
Curvilinear Inflated Balloon
Lumens Can Anesthetize Vocal Cords
Multi-Use Lumens (Tri-Lumen)
Height-Based Color Indicators
Patented Jet Angle on Tube
Rapid Deployment (<10 seconds)

Strategic Representation

Amnea Corp is exclusively represented by Vikings M&A for acquisition discussions and strategic partnerships.

Mark Ajamian, Partner
majamian@vikingmergers.com
202.599.4470
Dan Wilson, Partner
dwilson@vikingmergers.com
919.230.0775
Paul Prestegaard, Senior Advisor
paul@vikingmergers.com
804.215.5775

Open to full acquisition, majority sale, or structured partnership arrangements

Ready to Discuss This Opportunity?

For investor inquiries, acquisition discussions, or partnership opportunities,
contact Vikings M&A or reach out directly through our advisory team.